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. 2021 Mar 24;94(5):318–326. doi: 10.1016/j.anpede.2020.12.011

Table 2.

Frequency of different clinical manifestations in children with confirmed SARS-CoV-2 infection versus children with unconfirmed suspected infection.

Presentation SARS-CoV-2 infection, n = 33
No infection, n = 93
P
Sign or symptom Frequency Percentage Frequency Percentage
Fever
 At onset of symptoms 10 30.3 36 38.7 .389
 During the course of disease 18 54.5 75 80.7 .008



Headache
 At onset of symptoms 0 0.0 3 3.2 NC
 During the course of disease 14 42.4 18 19.4 .009



Cough
 At onset of symptoms 2 6.1 2 2.2 NC
 During the course of disease 11 33.3 39 41.9 .416



Asthenia
 At onset of symptoms 1 3.0 1 1.1 NC
 During the course of disease 11 33.3 30 32.3 1.000



Diarrhoea
 At onset of symptoms 0 0.0 11 11.8 NC
 During the course of disease 9 27.3 19 20.4 .467



Myalgia
 At onset of symptoms 0 0.0 2 2.2 NC
 During the course of disease 9 27.3 20 21.5 .482



Breathing difficulty
 At onset of symptoms 4 12.1 3 3.2 NC
 During the course of disease 7 21.2 28 30.1 .370



Cutaneous manifestations
 At onset of symptoms 0 0.0 1 1.1 NC
 During the course of disease 7 21.2 16 17.2 .607



Odynophagia
 At onset of symptoms 2 6.1 6 6.5 NC
 During the course of disease 6 18.2 27 29 .257



Chills
 At onset of symptoms 3 9.1 19 20.4 NC
 During the course of disease 6 18.2 21 22.6 .805



Wheezing
 At onset of symptoms 1 3.0 0 0.0 NC
 During the course of disease 6 18.2 30 32.3 .170



Anosmia/hyposmia
 At onset of symptoms 0 0.0 1 1.1 NC
 During the course of disease 5 15.2 3 3.2 .029



Rhinorrhoea
 At onset of symptoms 4 12.1 1 1.1 NC
 During the course of disease 4 12.1 11 11.8 1.000



Dysgeusia
 At onset of symptoms 1 3.0 0 0.0 NC
 During the course of disease 4 12.1 6 6.5 .288



Abdominal pain
 At onset of symptoms 0 0.0 5 5.4 NC
 During the course of disease 2 6.1 25 26.9 .012



Vomiting
 At onset of symptoms 0 0.0 1 1.1 NC
 During the course of disease 0 0.0 16 17.2 .011

Ordered by frequency in children with SARS-CoV-2 infection.

NC: not calculated due to the sample size.