Fig. 1.

Clinical images of Fuchs endothelial corneal dystrophy (FECD). A. Edema of the central cornea due to FECD. B. Retro-illumination photograph of a cornea with FECD showing numerous guttae that give a stippled appearance. C. Periodic acid-Schiff (PAS)-stained cross-section of normal cornea (endothelial cells, arrow; Descemet's membrane, asterisk). D. PAS-stained cross-section of cornea with FECD showing posterior elevations (guttae, arrows) arising from the thickened Descemet membrane (asterisk). E. In vivo confocal image of normal corneal endothelial cells show a regular hexagonal pattern. F. In vivo confocal image of FECD corneal endothelium with disrupted hexagonal cell pattern. Dark areas represent guttae.