Table 3.

Plasma alprazolam levels in rhesus monkeys (N=4) treated chronically with alprazolam or saline.

Day	Treatment	Plasma alprazolam (mean ng/mL ± SEM)
2	Alprazolam (1.0 mg/kg/4 h, i.v.)	722.8 ± 66.9
10	Alprazolam (1.0 mg/kg/4 h, i.v.)	669.8 ± 99.3
17	Alprazolam (1.0 mg/kg/4 h, i.v.)	781.5 ± 94.5
38	Alprazolam (1.0 mg/kg/4 h, i.v.)	718.3 ± 96.9
40	Saline (0.2 mL/kg/4 hr)	0.26 ± 0.16*

^*N=3 (Below detection limit in one monkey).

Alprazolam levels in plasma were determined according to Greenblatt et al. (1990).