Figure 7.

Magnitudes of change in unmodified lysine residues at individual lysyl hydroxylation sites of type I collagen between P3H3, LH1, and CypB null mice compared with WT. The schematic diagram and heat map show the magnitudes of change of unmodified lysine residues at individual lysyl hydroxylation sites. The change was calculated by [the value of unmodified lysine (%) in null mice] − [the value of unmodified lysine (%) in WT mice]. The values of the skin and tendon in Tables 4 and 5 were used to calculate the changes in P3H3 null and LH1 null mice. The values of unmodified lysine for CypB null mice tendon and skin were obtained from references (28, 29), respectively.