Table 3.
The melting temperature of each fraction folded in skin type I collagen from P3H3 and LH1 null mice relative to their wild-type controls
| Fraction folded | P3H3 |
LH1 |
||||
|---|---|---|---|---|---|---|
| Temperature (°C) |
p value | Temperature (°C) |
p value | |||
| Null (4) | WT (4) | Null (3) | WT (3) | |||
| 0.9 | 33.0 ± 0.41 | 34.5 ± 1.44 | 0.09 | 37.0 ± 0.31 | 37.4 ± 0.96 | 0.45 |
| 0.8 | 36.1 ± 0.79 | 37.2 ± 0.39 | 0.059 | 38.0 ± 0.08 | 38.8 ± 0.16 | 1.21E-04 |
| 0.7 | 37.5 ± 0.24 | 38.1 ± 0.27 | 1.68E-03 | 38.4 ± 0.06 | 39.3 ± 0.04 | 2.92E-07 |
| 0.6 | 38.0 ± 0.09 | 38.5 ± 0.19 | 2.08E-03 | 38.7 ± 0.04 | 39.6 ± 0.07 | 5.65E-07 |
| 0.5 | 38.3 ± 0.13 | 38.8 ± 0.11 | 7.30E-04 | 38.9 ± 0.05 | 39.9 ± 0.04 | 1.22E-07 |
| 0.4 | 38.6 ± 0.08 | 39.2 ± 0.12 | 3.35E-04 | 39.2 ± 0.05 | 40.1 ± 0.01 | 1.76E-08 |
| 0.3 | 38.9 ± 0.07 | 39.5 ± 0.15 | 5.45E-04 | 39.3 ± 0.05 | 40.4 ± 0.05 | 1.59E-07 |
| 0.2 | 39.2 ± 0.07 | 39.9 ± 0.22 | 8.99E-04 | 39.6 ± 0.05 | 40.7 ± 0.04 | 5.68E-08 |
| 0.1 | 39.6 ± 0.19 | 40.5 ± 0.28 | 1.97E-03 | 39.9 ± 0.07 | 41.1 ± 0.06 | 2.09E-07 |
Values are given as means ± S.D. The number in the bracket next to the genotypes indicates biological replicates.