Table III:

5-year Overall Survival in HPV-associated OPSCC adjusted for demographics, stage, tobacco, and alcohol

	Addition of tobacco and alcohol use*
	Hazard Ratio	95% CI	P-Value
Black (vs. white)	4.1	1.5 – 11.4	0.007
Age Category (Relative to < 50)
50–65	0.9	0.4 – 2.0	0.773
65+	1.4	0.5 – 3.9	0.531
Female sex (relative to male)	0.8	0.3 – 2.0	0.694
T Stage (relative to T1)
T2	0.8	0.3 – 1.9	0.546
T3	1.5	0.6 – 4.0	0.400
T4	2.5	1.0 – 6.3	0.053
Nodal disease (relative to N0)	1.7	0.7 – 4.2	0.267
Distant Metastases (relative to M0)	4.6	0.6 – 36.5	0.154
Smoking (> 10 pack-years)	1.0	0.5 – 2.2	0.903
Alcohol use (any vs. none)	1.6	0.5 – 4.6	0.403

^*Model adjusted for race, age, sex, T stage, nodal disease, distant metastases, smoking, and alcohol use