Skip to main content
. Author manuscript; available in PMC: 2022 Feb 5.
Published in final edited form as: Schizophr Res. 2021 Feb 5;228:394–402. doi: 10.1016/j.schres.2020.12.022

Table 3:

Brain regions showing a correlation in the SZ Group (A) between activation amplitude in the Word Valence Type contrast and PANSS Excitement/Hostility scores, and (B) between activation amplitude in the Task period contrast and PANSS Cognitive scores. Activation clusters exceeding whole-brain pcorrected<0.05 are listed, along with the corresponding Brodmann area, MNI peak coordinates, peak z-score, corrected p-value, and cluster size. L - left; R - right.

(A) Correlation of Excitement/Hostility scores and activation in Negative vs Neutral words contrast
Brain region Brodmann area Peak coordinate (MNI space) Peak Z p-corrected (whole brain) Cluster size (mm3)
x y z
Positive correlation
L middle frontal gyrus 10/11/46 −30 57 9 3.758 0.04 4293
R anterior cingulate cortex 32 15 45 15 3.723 0.045 4266
L temporal pole/ superior temporal gyrus 21/38 −57 3 −9 3.86 0.029 1269
L superior occipital gyrus 19 −21 −84 30 3.686 0.05 8532
L middle occipital gyrus 19 −36 −78 12 4.065 0.014 2241
R middle occipital gyrus 37 39 −72 9 4.119 0.012 1998
Negative correlation
L inferior frontal gyrus, pars opercularis 44 −63 18 24 4.24 0.012 945
L middle temporal gyrus 22 −57 −39 3 3.9 0.025 2862
R ventromedial prefrontal cortex 11 15 21 −33 4.23 0.013 4266
(B) Correlation of Cognitive Impairment scores and activation in Early vs Late period contrast
Brain region Brodmann area Peak coordinate (MNI space) Peak Z p-corrected (whole brain) Cluster size (mm3)
x y z
Positive correlation
R frontal superior orbital gyrus 11 18 30 −24 3.857 0.029 1053
R amygdala 34 21 3 −15 3.956 0.021 4941
L insula 13 −36 −9 0 4.221 0.008 5805
R insula 13 36 12 3 4.095 0.013 8262
Negative correlation
L cerebellum −6 −51 −42 3.667 0.053 4050