Table III.
Role of UCA1 in clinical correlation and prognosis of diseases.
| Disease | Upregulation/downregulation | Clinical correlation | (Refs.) |
|---|---|---|---|
| Renal cancer | Upregulation | Degree of differentiation, TNM stage and lymph node metastasis | (11,107) |
| SLE | Upregulation | SLEDAI | (18) |
| CRC | Upregulation | Tumor size, tumor stage, lymph node infiltration, lymph node metastasis and OS | (22,24) |
| HCC | Upregulation | Tumor stage, TNM stage, Microvascular infiltration and OS | (23) |
| GC | Upregulation | TNM stage, tumor stage, lymph node infiltration, lymph node metastasis and OS | (8,9) |
| Tongue cancer | Upregulation | TNM staging, lymph node metastasis, lymph node infiltration and OS | (46) |
| Osteosarcoma | Upregulation | Tumor stage, tumor size and OS | (72) |
| OSCC | Upregulation | TNM stage, lymph node metastasis and OS | (108) |
| PTC | Upregulation | Tumor size, tumor stage, lymph node metastasis and OS | (26,82) |
| MM | Upregulation | OS | (98,102) |
| PC | Upregulation | Tumor stage and OS | (27,105) |
| LSCC | Upregulation | Lymph node metastasis and OS | (110) |
| NSCLC | Upregulation | TNM stage, tumor size and OS | (111) |
| PCa | Upregulation | Edmondson-Steiner grade, TNM stage and lymph node metastasis | (112,114) |
| Epilepsy | Upregulation | Classification of epilepsy | (120) |
| Glioma | Upregulation | TNM stage, tumor size, lymph node metastasis and OS | (109) |
| Cholangiocarcinoma | Upregulation | TNM stage, tumor stage, lymph node infiltration, lymph node metastasis, RFS and OS | (10) |
| OC | Upregulation | TNM stage, lymph node metastasis and OS | (128) |
| NPC | Upregulation | Tumor stage, lymph node metastasis and OS | (113) |
| ACC | Upregulation | TNM stage and lymph node metastasis | (124) |
| LUAD | Upregulation | TNM stage, lymph node metastasis, RFS and OS | (28) |
| Melanoma | Upregulation | Tumor stage and lymph node metastasis | (106) |
| EC | Upregulation | Degree of differentiation, TNM stage, lymph node metastasis and OS | (125) |
UCA1, urothelial carcinoma associated 1; ACC, adrenal cortical carcinoma; CRC, colorectal cancer; EC, esophageal cancer; GC, gastric cancer; HCC, hepatocellular carcinoma; LSCC, laryngeal squamous cell carcinoma; LUAD, lung adenocarcinoma; MM, multiple myeloma; NPC, nasopharyngeal carcinoma; NSCLC, non-small cell lung cancer; OC, ovarian cancer; OS, overall survival; OSCC, oral squamous cell carcinoma; PC, pancreatic cancer; PCa, prostate cancer; PTC, papillary thyroid carcinoma; RFS, relapse-free survival; SLEDAI, systemic lupus erythematosus disease activity index; TNM, tumor-node-metastasis.