Table I.
BMPR2 expression in cancer vs. normal tissue in the Oncomine database.
| Cancer | P-value | Fold-change | Rank, % | Sample size | (Refs.) |
|---|---|---|---|---|---|
| Brain and CNS cancer | |||||
| Oligodendroglioma | 5.19×10−8 | 2.132 | 5 | 73 | Sun et al (70) |
| Glioblastoma | 6.73×10−4 | −3.216 | 7 | 15 | TCGAa |
| Breast cancer | |||||
| Invasive ductal breast carcinoma | 1.60×10−2 | 2.896 | 6 | 25 | Turashvili et al (71) |
| Invasive lobular breast carcinoma | 1.40×10−2 | −2.075 | 3 | 25 | Turashvili et al (71) |
| Colorectal cancer | |||||
| Rectal mucinous adenocarcinoma | 2.10×10−4 | 2.171 | 5 | 9 | Kaiser et al (72) |
| Esophagus cancer | |||||
| Esophageal adenocarcinoma | 6.11×10−4 | 2.529 | 9 | 5 | Hao et al (73) |
| Head and neck cancer | |||||
| Floor of the mouth carcinoma | 1.61×10−4 | 3.473 | 7 | 5 | Pyeon et al (74) |
| Kidney cancer | |||||
| Clear cell sarcoma | 4.44×10−4 | 2.479 | 4 | 17 | Cutcliffe et al (75) |
| Renal oncocytoma | 1.00×10−3 | 2.37 | 6 | 9 | Yusenko et al (76) |
| Chromophobe renal cell carcinoma | 7.00×10−3 | −2.961 | 6 | 9 | Yusenko et al (76) |
| Leukemia | |||||
| Chronic lymphocytic leukemia | 2.96×10−13 | 3.465 | 1 | 12 | Alizadeh et al (77) |
| Chronic lymphocytic leukemia | 1.69×10−10 | 2.589 | 1 | 39 | Rosenwald et al (78) |
| Chronic lymphocytic leukemia | 1.23×10−92 | 3.446 | 1 | 448 | Haferlach et al (79) |
| Chronic lymphocytic leukemia | 1.00×10−3 | 2.188 | 7 | 3 | Rosenwald et al (80) |
| Chronic lymphocytic leukemia | 1.50×10−6 | 3.205 | 5 | 34 | Basso et al (81) |
| T cell prolymphocytic leukemia | 6.04×10−4 | −2.972 | 3 | 6 | Dürig et al (82) |
| Lung cancer | |||||
| Lung adenocarcinoma | 5.66×10−17 | −2.281 | 3 | 43 | Hou et al (83) |
| Large cell lung carcinoma | 1.08×10−12 | −2.775 | 3 | 19 | Hou et al (83) |
| Squamous cell lung carcinoma | 6.86×10−17 | −3.47 | 3 | 27 | Hou et al (83) |
| Lymphoma | |||||
| Follicular lymphoma | 7.00×10−3 | 2.425 | 5 | 6 | Basso et al (81) |
| Germinal center B cell-like diffuse large | 3.31×10−6 | 2.934 | 3 | 9 | Compagno et al (84) |
| B cell lymphoma | |||||
| Follicular lymphoma | 3.99×10−9 | 3.239 | 9 | 38 | Compagno et al (84) |
| Myeloma | |||||
| Non-neoplastic nevus | 4.00×10−3 | −2.388 | 7 | 9 | Haqq et al (85) |
| Pancreatic cancer | |||||
| Pancreatic ductal adenocarcinoma | 1.82×10−12 | 2.055 | 2 | 39 | Badea et al (86) |
| Pancreatic adenocarcinoma | 1.82×10−12 | 3.078 | 6 | 12 | Iacobuzio-Donahue et al (87) |
| Prostate cancer | |||||
| Prostate carcinoma | 2.70×10−2 | 4.768 | 8 | 15 | Luo et al (88) |
| Sarcoma | |||||
| Clear cell sarcoma of the kidney | 4.44×10−4 | 2.479 | 4 | 14 | Cutcliffe et al (75) |
| Gastrointestinal stromal tumor | 3.69×10−4 | 2.62 | 7 | 6 | Cho et al (89) |
| Other | |||||
| Skin basal cell carcinoma | 2.51×10−5 | 2.144 | 3 | 15 | Riker et al (90) |
| Teratoma, NOS | 2.48×10−08 | 2.606 | 4 | 14 | Korkola et al (91) |
| Skin basal cell carcinoma | 5.08×10−06 | −2.996 | 1 | 15 | Riker et al (90) |
a
TCGA, The Cancer Genome Atlas, No Associated Paper, http://tcga-data.nci.nih.gov/tcga/; CNS, central nervous system; NOS, not otherwise specified.