Figure 8.

Expression of nicotinic acetylcholine receptors (nAChRs) in normal mice. Normal mice express several nAChRs (green) in the kidney cortex, as assessed by immunofluorescence including proximal tubular (PT; red) and distal tubular (DT; red) expression as well as glomerular expression. DAPI was used as the nuclear stain. We determined that mice express α₄-, α₅-, α₆-, α₇-, β₂-, β₃-, and β₄-nAChRs. Of these, α₄ and α₅ had predominantly glomerular expression, whereas the rest had predominantly tubular expression.