Figure 7: Effect of oxycodone treatment and withdrawal on oligodendrocytes differentiation and proliferation:
Illustration showing expression of oligodendrocyte lineage specific markers in differentiation process from oligodendrocytes precursor cells (OPCs) to mature myelinating oligodendrocytes (A); Bar graph showing qPCR analysis of NG2 (B, C); Olig2 (D, E); Sox10 (F, G) and MBP (H, I) mRNA in the PFC and NAc of saline, oxycodone and withdrawal treated male and female mice. *<0.05, **<0.005, ***<0.0001; n=10–15/group.
