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. Author manuscript; available in PMC: 2021 Mar 24.
Published in final edited form as: Angew Chem Int Ed Engl. 2020 Sep 28;59(49):22017–22022. doi: 10.1002/anie.202010861

Figure 3.

Figure 3.

Reversal of RNA crosslinks. A) Structures of tested phosphines. B) PAGE analysis of BINARI 3 crosslinked RNA 1 and THPP reversal of crosslinked RNA 1. C) Amount of uncrosslinked- monofunctionalized and crosllinked RNA 1 obtained after incubation with each of three phosphines. D) Yields of the crosslink reversal reactions at varied concentrations of THPP. E) Amount of uncrosslinked RNA obtained as a function of incubation times with THPP. Error bars represent s.d. of triplicate experiments.