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. 2021 Mar 23;21:160. doi: 10.1186/s12893-021-01158-7

Table 3.

Multivariate analysis of factors predicting pCR after NAC

Parameters Odds ratio 95% Confidence interval P value
Clinical T stage
 T1 vs T4 5.304 2.222–12.664  < 0.001
 T2 vs T4 1.808 1.065–3.067 0.028
 T3 vs T4 1.216 0.648–2.282 0.541
Clinical N stage
 N0 vs N2 2.434 1.201–4.933 0.014
 N1 vs N2 3.344 2.196–5.090  < 0.0001
SBR grade
 2/1 2.327 0.765–7.073 0.137
 3/1 3.312 1.101–9.963 0.033
Subtype
 HR + /HER2 + vs  HR + /HER2− 4.851 2.862–8.221  < 0.0001
 HR−/HER2 + vs HR + / HER2− 8.781 5.146–14.986  < 0.0001
 HR−/HER2− vs HR + /HER2− 4.868 2.722–8.706  < 0.0001

HR hormone receptor, HER-2 human epidermal growth factor receptor 2, NAC neoadjuvant chemotherapy, pCR pathological complete response