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. 2021 Mar 23;21:304. doi: 10.1186/s12885-021-08049-3

Table 1.

Characteristics of patients in the study population

Number (%)
Total Number of Patients 130
Age, years (median, range) 74 (32–97)
Sex (Male/Female) 71 (54.6)/59 (45.4)
Primary Cancer Site
 Lung 31 (23.8)
 Colon 26 (20.0)
 Pancreas 12 (9.2)
 Liver 7 (5.4)
 Stomach 7 (5.4)
 Esophagus 5 (3.8)
 Breast 5 (3.8)
 Ovary 4 (3.1)
 Uterine 4 (3.1)
 Prostate 3 (2.3)
 Other 23 (17.7)
 Unknown 3 (2.3)
Metastasis (total number)
 Liver 54 (41.5)
 Lung 52 (40.0)
 Bone 40 (30.8)
 Brain 14 (10.8)
PPS
  ≥ 70 20 (15.4)
 40–60 74 (56.9)
  ≤ 30 29 (22.3)
 Unknown 7 (5.4)
Survival, days (median, range) n = 109 18 (2–193)
QLQ-C15-PAL (median (Q1, Q3), mean (± SD))
 Physical Functioning (n = 125) 33.3 (20.0, 46.7), 37.0 ± 25.1
 Emotional Functioning (n = 129) 66.7 (41.7, 83.3), 63.2 ± 28.3
 Dyspnea 33.3 (0.0, 66.7), 39.5 ± 34.4
 Pain (n = 129) 50.0 (16.7, 66.7), 47.3 ± 34.0
 Insomnia 33.3 (0.0, 66.7), 40.0 ± 36.0
 Appetite Loss 66.7 (33.3, 100), 57.7 ± 38.4
 Constipation (n = 128) 33.3 (0.0, 66.7), 37.0 ± 35.3
 Fatigue (n = 129) 66.7 (44.4, 100), 63.8 ± 29.7
 Nausea/Vomiting 0.0 (0.0, 16.7), 18.7 ± 29.6
 QOL (n = 124) 50.0 (16.7, 50.0), 38.7 ± 27.1
Inflammatory Biomarkers (median, range) n = 126
 CRP (mg/dL) 3.9 (<  0.1–32.1)
 Alb (g/dL) 2.6 (1.2–3.9)
 NLR (n = 122) 7.6 (0.6–187)

Alb albumin, CRP C-reactive protein, NLR neutrophil-lymphocyte ratio, PPS Palliative Performance Scale, QLQ-C15-PAL European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 15 Palliative Care, QOL quality of life

In the QLQ-C15-PAL, patients rated their symptoms using a 4-point scale (1 = not at all, 2 = a little, 3 = quite a bit, 4 = very much) for two functional domains and 7 symptom domains, and a 7-point scale (range: 1 = very poor to 7 = excellent) for overall QOL. All scale scores were linearly transformed, and the resultant scores ranged from 0 to 100. Q1: first quarter (25% quartile), Q3: third quarter (75% quartile), SD: standard deviation