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. 2021 Mar 21;13:1759720X21999564. doi: 10.1177/1759720X21999564

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© The Author(s), 2021

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 3. — Forest plots of network meta-analysis of all trials for efficacy and safety. A. ACR20. B. DAS28. C. HAQ-DI. D. Discontinuations for AEs. Drugs compared with placebo, which was the reference compound.

ACR20, American College of Rheumatology 20% response; AEs, adverse events; Crl, credible interval; csDMARDs, conventional synthetic disease-modifying antirheumatic drugs; DAS28, Disease Activity Score in 28 joints; HAQ-DI, Health Assessment Questionnaire–Disability Index; OR, odds ratio; WMD, weighted mean difference.