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. 2021 Mar 21;12:20406223211002969. doi: 10.1177/20406223211002969

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© The Author(s), 2021

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 2. — TFAS at the group level for C9orf72 fALS patients compared with controls. TFAS demonstrated significant regional FA reductions in tracts of callosal areas II and III in C9orf72 fALS patients compared with matched controls and FA reductions in tracts of callosal area III in sporadic ALS patients. Error bars are SEM.

*p < 0.05, **p < 0.001 (Bonferroni-corrected).

ALS, amyotrophic lateral sclerosis; FA, fractional anisotropy; fALS, familial ALS; SEM, standard error of the mean; TFAS, tractwise fractional anisotropy statistics.