Table 1.
Bivariate and multivariate analysis of factors associated with a positive SARS-CoV-2 serology among 1,996 healthcare workers from a private hospital in São Paulo, Brazil
| Seropositive N = 110 (%) | Seronegative N = 1886 (%) | Odds ratio (95%CI) | P-value | Adjusted odds ratio | Adjusted 95% confidence interval | P-value | |
|---|---|---|---|---|---|---|---|
| Male gender | 42 (38) | 536 (28) | 1,56 (1,04 - 2,32) | 0.03 | 1,54 | 1.03-2.32 | .035 |
| Age (years) | |||||||
| Mean | 37 | 36 | |||||
| <=30 | 26 | 508 | 0.84 (0.53-1.32) | .44 | |||
| 31-40 | 47 | 838 | 0.93 90.63-1.38) | .73 | |||
| 41-50 | 32 | 447 | 1.32 90.86-2.02) | .20 | |||
| 51-60 | 5 | 86 | 0.99 (0.40-2.50) | .99 | |||
| 61+ | 0 | 7 | |||||
| Presence of comorbidities | 13 (12) | 313 (17) | 0.67 (0.37-1.21) | .19 | |||
| Hypertension | 6 | 133 | 1,16 (0.38-3.53) | .79 | |||
| Diabetes | 1 | 24 | 1.00 (0.13-8.04) | .99 | |||
| Obesity | 3 | 103 | 0.61 (0.16-2.27) | .46 | |||
| Pulmonary disease | 5 | 80 | 1.82 (0.58-5.73) | .30 | |||
| Immunosuppression | 0 | 15 | |||||
| Professional category | |||||||
| Physician | 3 (2) | 134 (98) | 0.37 (0.11-1.18) | .08 | |||
| Administrative job | 19 (5) | 388 (95) | 0.80 (0.48-1.34) | .40 | |||
| Cleaning | 11 (12) | 82 (88) | 2.44 (1.26-4.73) | .006 | 2.23 | 1.12-4.44 | .023 |
| Lab/radiology technician | 4 (6) | 62 (94) | 1.11 (0.39-3.10) | .84 | |||
| Nurse | 19 (5) | 329 (95) | 0.98 (0.59-1.64) | .96 | |||
| Food service worker | 4 (9) | 42 (91) | 1.66 (0.58-4.70) | .34 | |||
| Nutritionist | 0 (0) | 37 (100) | .14 | ||||
| Speech therapist | 0 (0) | 6 (100) | .55 | ||||
| Nursing assistant | 34 (6) | 560 (94) | 1.05 (0.69-1.60) | .78 | |||
| Physiotherapist | 5 (4) | 113 (96) | 0.74 (0.30-1.87) | .53 | |||
| Pharmacist | 4 (6) | 58 (94) | 1.18 (0.42-3.33) | .74 | |||
| Biomedic | 4 (7) | 56 (93) | 1.23 (0.43-3.46) | .69 | |||
| Others | 3 (14) | 19 (86) | 2.75 (0.80-9.45) | .09 | |||
| Previous negative RT-PCR SARS-CoV 2 | 27 (25) | 462 (25) | 1 (0.64-1.57) | .99 | |||
| Type of hospital exposure | |||||||
| high risk | 76 (6) | 1283 (94) | 1.05 (0.70-1.60) | .82 | |||
| medium risk | 16 (4) | 346 (96) | 0.76 (0.44-1.30) | .31 | |||
| low risk | 18 (7) | 257 (93) | 1.24 (0.74-2.09) | .42 | |||
| Working or worked at COVID-19 Units | 76 (69) | 1267 (67) | 1.09 (0.72-1.65) | .68 | 1.079 | 0.706-1.647 | .726 |
| Works in other hospital | 17 (15) | 273 (14) | 1.08 (0.63-1.84) | .77 | |||
| Working in COVID-19 Units at other hospital | 14 (13) | 183 (10) | 1.36 (0.76-2.42) | .30 | |||
| Contact with COVID-19 confirmed case (not patients) | |||||||
| Co-worker | 98 (89) | 1622 (86) | 1.33 (0.72-2.45) | .36 | |||
| Household | 10 (9) | 139 (7) | 1.26 (0.65-2.46) | .50 | |||
| Social | 46 (42) | 779 (41) | 1.02 (0.69-1.51) | .92 | |||
| Place of meals | |||||||
| Hospital canteen | 100 (91) | 1645 (88) | 1.46 (0.75-2.84) | .25 | |||
| Home | 10 (9) | 241 (12) | 0.68 (0.35-1.33) | .26 | |||
| Type of transport to hospital | |||||||
| Public transport (Bus. metro) | 69 (63) | 1111 (59) | 1.17 (0.79-1.75) | .43 | 1.103 | 0.731-1.665 | .640 |
| Individual (car. bicycle. motorcycle. on foot) | 41(37) | 775 (41) | 0.85 (0.57-1.27) | .43 | |||
| Presence> 1 person per bedroom at home | 42 (38) | 696 (37) | 1,06 (0,71-1,57) | .79 | |||
| Presence of people > 60 years at home | 22 (20) | 368 (20) | 1.03 (0.64-1.67) | .90 | |||
| Presence of children at home | 45 (40) | 770 (41) | 1.00 (0.68-1.48) | .98 |