Table 1.
Variable | CAPA (n = 16) | Controls (n = 67) | P-value |
---|---|---|---|
Age (years), mean (SD) | 64 (10) | 55 (15) | <0.001 |
Female sex | 5(31.25) | 15 (22) | 0.47 |
PaFIO2, median (IQR) | 122 (84–166) | 108 (82–160) | 0.76 |
Comorbidities | |||
Overweight | 8 (50) | 33 (49) | 0.39 |
Obesity | 6 (38) | 19 (28) | 0.39 |
COPD | 1 (6) | 3 (4) | 0.77 |
Hypertension | 4 (25) | 22 (33) | 0.57 |
Diabetes mellitus | 5 (31) | 13 (19) | 0.30 |
Cancer | 3 (19) | 3 (4) | 0.05 |
Laboratory data, median (IQR) | |||
Leucocytes | 9 (6–10) | 8 (6–12.5) | 0.94 |
Lymphocytes | 0.93 (0.62–1.27) | 0.88 (0.54–1.10) | 0.65 |
Platelets | 205 (135–257) | 192 (139–298) | 0.66 |
D-Dimer | 1088 (714–2795) | 1072 (648–2085) | 0.68 |
C reactive protein | 18 (5–26) | 17 (9–30) | 0.39 |
Interleukin 6 | 15 (9–88) | 44 (12.5–77) | 0.60 |
Ferritin | 1756 (1027–2387) | 1178 (722–2089) | 0.18 |
Severity scales | |||
NEWS, mean (SD) | 7.1 (2.47) | 6.84 (2.45) | <0.001 |
CALL, median (IQR) | 10 (8.5–11.5) | 9 (7–11) | 0.21 |
MuLBSTA, median (IQR) | 12 (11–12) | 9 (7–12) | 0.26 |
Positive bacterial isolates | |||
CVC culture | 5 (31) | 4 (6) | 0.01 |
Endotracheal tube culture | 3 (19) | 7 (10) | 0.39 |
Sputum culture | 1 (6) | 3 (4) | 1.00 |
Here we show the comparison of the baseline characteristics among patients with and without CAPA. All values are N(%) unless otherwise noted.
COPD: Chronic obstructive pulmonary disease, CRP: C-reactive protein, CVC: Central venous catheter, IL-6: Interleukin-6.