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. 2021 Mar 19;14:957–965. doi: 10.2147/IJGM.S294392

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© 2021 Fu et al.

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Schematic map of theHERVW gene. The downward arrow and number indicate the 10 CpG sites and position in the methylated fragment, respectively. The TSE is the trophoblast-specific enhancer region located directly upstream of the 5ʹLTR U3 region. In addition, important cis-acting elements are highlighted below the methylated fragment.