Table 3.
Incidence of RPE Tear Across Retrospective Case Series With Anti-VEGF Treatment
Study | Treatment | Duration, Months | Eyes, n | Incidence of RPE Tear Across Treatment Groups, n (%) | Incidence of PED Across Treatment Groups, n (%) | Incidence of RPE Tear in Patients With PED, n (%) |
Chan et al11 | Bevacizumab* | 12 | 1,064 | 22 (2.2) | 123 (11.6) | 21 (17.1) |
Gelisken et al30 | Bevacizumab* | 12 | 409 | 15 (3.7) | NS | NS† |
Leitritz et al31 | Bevacizumab* | NA | 393 | 15 (3.8) | NS | 14.8 |
Empeslidis et al12 | Ranibizumab or bevacizumab* | 18 | 628‡ | 17 (2.7) | NS | NS |
Konstantinidis et al32 | Ranibizumab | 24 | 74 | 4 (5.4) | NA | 7 (12.3) |
Bevacizumab is not licensed for the treatment of retinal diseases.
Patients with serious PED were excluded.
Number of patients.
NA, not applicable; NS, not stated.