Table 3.
Demographic, clinical and biochemical parameters of COVID-19 patients stratified by invasive mechanical ventilation.
| Invasive mechanical ventilation |
||||
|---|---|---|---|---|
| All patients (n = 107) | Yes (n = 50) | No (n = 57) | Pa | |
| Age (years) | 55.8 ± 13.6 | 58.4 ± 12.1 | 53.4 ± 14.4 | 0.055 |
| Male (%) | 55.1 | 82.0 | 56.1 | 0.004 |
| Body mass index (Kg/m2) | 27 [26–31] | 28 [26–31] | 27 [25–31] | 0.672 |
| Type 2 diabetes mellitus (%) | 38.3 | 52.9 | 31.5 | 0.397 |
| Hypertension (%) | 45.8 | 55.9 | 41.1 | 0.093 |
| Alanine aminotranferase (U/L) | 49 ± 41 | 46 ± 35 | 51 ± 45 | 0.546 |
| Aspartate aminotranferase (U/L) | 47 ± 40 | 53 ± 41 | 42 ± 38 | 0.166 |
| Alkaline phosphatase (U/L) | 97 ± 51 | 100 ± 46 | 94 ± 55 | 0.527 |
| Lactate deshidrogenase (U/L) | 275 [224–383] | 334 [260–436] | 243 [194–296] | 0.080 |
| Total bilirubin (mg/dL) | 0.60 [0.44–0.92] | 0.55 [0.38–1.02] | 0.69 [0.53–0.87] | 0.552 |
| Albumin (g/dL) | 2.81 [2.53–3.22] | 2.54 [2.36–2.79] | 3.18 [2.84–3.36] | <0.001 |
| C reactive protein (mg/L) | 97.6 [27.9–204.1] | 135.5 [55.1–231.3] | 73.9 [21.4–153.0] | 0.013 |
| D-Dimer (μg/mL) | 0.51 [0.24–0.90] | 0.75 [0.49–1.79] | 0.29 [0.17–0.64] | <0.001 |
| Fibrinogen (g/mL) | 5.01 ± 1.33 | 5.18 ± 1.30 | 4.85 ± 1.34 | 0.201 |
| Ferritin (g/mL) | 634 [355–998] | 771 [404–1142] | 556 [336–853] | 0.041 |
| Lymphocytes % | 11.8 [6.0–16.3] | 8.4 [3.3–13.3] | 14.6 [9.5–14.6] | <0.001 |
| Neutrophils % | 43.4 ± 40.5 | 39.1 ± 43.8 | 47.1 ± 37.3 | 0.313 |
| Leucocytes ×103/μL | 7.5 [5.5–11.4] | 9.4 [6.4–14.4] | 6.0 [4.7–8.8] | <0.001 |
| Platelets ×103/μL | 288.0 ± 125.6 | 291.1 ± 119.3 | 285.3 ± 131.8 | 0.813 |
| International normalized ratio | 1.21 ± 0.36 | 1.19 ± 0.22 | 1.22 ± 0.45 | 0.752 |
| Mortality (%)b | 27.5 | 47.9 | 9.3 | <0.001 |
Data are shown as mean ± standard deviation, median [interquartile range] or percentage.
a
Student's t-test, Mann Whitney's U test or Chi square test as appropriate.
b
This analysis was made in 102 patients.