Table 1.

Baseline characteristics of patients according to the presence of CAA-unrelated and CAA-related ICH

	CAA-unrelated ICH (n = 56)	CAA-related ICH (n = 48)	p value
Age, years	59.6±13.9	70.9±10.2	0.007
Male sex	38 (68.9)	24 (50.0)	0.064
Hypertension	40 (71.4)	36 (75.0)	0.825
Dyslipidemia	27 (48.2)	28 (58.3)	0.303
Diabetes	10 (17.9)	11 (22.9)	0.522
Antiplatelet therapy	7 (12.5)	9 (18.8)	0.378
Anticoagulation therapy	9 (16.1)	10 (20.8)	0.531
Admission Glasgow Coma Scale	15 (13–15)	14 (14–15)	0.974
Admission systolic blood pressure, mm Hg	155 (133–174)	144 (132–153)	0.029
Admission diastolic blood pressure, mm Hg	87 (69–101)	75 (67–83)	0.006
Admission glucose, mg/dL	120 (109–149)	109 (103–131)	0.040
Admission INR	1.0 (1.0–1.2)	1.1 (1.0–1.2)	0.880
Admission platelet count, /µL	211 (153–254)	201 (167–230)	0.719
ICH location
Lobar	11 (19.6)	45 (93.8)	<0.001
Deep	33 (58.9)	0	<0.001
Infratentorial	12 (21.4)	3 (6.3)	0.047
Intraventricular rupture	14 (25.0)	14 (29.2)	0.633
Emergent neurosurgery	6 (10.7)	2 (4.2)	0.282
MRI findings
Age-related white matter changes score
Periventricular	1 (1–2)	2 (1–3)	0.107
Deep	1 (1–2)	2 (1–3)	0.142
Enlarged perivascular spaces score
Centrum semiovale	1 (1–2)	2.5 (1–3)	<0.001
Basal ganglia	2 (1–2)	1 (1–2)	0.119
Number of microbleeds
Lobar	0 (0–1)	5 (1–9)	<0.001
Basal ganglia	0 (0–2)	−	<0.001
Infratentorial	0 (0–1)	0 (0–1)	0.930
Cortical superficial siderosis	4 (7.1)	28 (58.3)	<0.001
Focal (≤3 sulci)	1 (1.8)	13 (27.1)	<0.001
Disseminated (>3 sulci)	3 (5.4)	15 (31.3)	0.001
30-day mortality	2 (3.6)	1 (2.1)	1.000
Follow-up, months	27 (21–43)	24 (14–43)	0.396
ICH recurrence	0	13 (27.1)	<0.001

Data is presented as n (%), mean ± SD, and median (interquartile range). CAA, cerebral amyloid angiopathy; ICH, intracerebral hemorrhage; INR, international normalized ratio; MRI, magnetic resonance imaging.