Table 1.
Patient No. | Age, years | Gender | Type of tumor | Tumor grading | Concurrent chemotherapy | Interval from RT to 1st follow-up visit1 | Interval from RT to onset of symptoms2 | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 49.7 | male | G1 SCC | T4a N0 M0 | Yes | 17.4 months | 16.0 months | |||||||
2 | 75.3 | female | <G1 SCC | T4a N0 M0 | No | 5.5 months | 4.0 months | |||||||
3 | 82.2 | male | G2/G3 SCC | T4a N0 M0 | No | 10.0 months | 4.0 months | |||||||
4 | 71.1 | female | G3 undifferentiated | T4a N0 M0 | Yes | 0.7 months | −0.3 months | |||||||
5 | 63.3 | male | G2 SCC | T4b N2b M0 | Yes | 0.3 months | −0.1 months | |||||||
6 | 59.4 | male | G1/G2 SCC | T4b N2c M0 | Yes | 2.8 months | 1.5 months | |||||||
7 | 60.7 | male | G1 SCC | T4a N2b M0 | Yes | 0.6 months | −0.1 months |
Patient No. | Complications |
Initial CDVA | Final CDVA | Surgery |
Systemic outcome | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
LMD | DED | NK | LSCD | CC | glaucoma | RR | CP | TK | AMT | tarsorrhaphy | ||||
1 | + | + | III | − | − | − | − | + | 6/12 | PL | + | − | − | deceased |
2 | + | + | III | − | + | − | − | + | 6/18 | HM | − | + | + | disease-free |
3 | + | + | I | + | + | + | + | − | 6/400 | PL (before | − | + | − | disease-free |
4 | + | + | III | + | + | + | − | + | 6/18 | evisceration) CF | + | + | disease-free | |
5 | + | + | III | + | + | − | − | + | 6/36 | 6/18 | + | + | + | disease-free |
6 | + | + | I | − | − | − | − | − | 6/9 | 6/6 | − | − | − | deceased |
7 | + | + | II | − | + | − | − | − | 6/9 | 6/9 | − | + | + | recurrence |
RT, radiotherapy; SCC, squamous cell carcinoma; CDVA, corrected-distance visual acuity; LMD, lid margin disease (including madarosis, meibomianitis, keratinization, and loss of meibomian glands); DED, dry eye disease; NK, neurotrophic keratopathy; LSCD, limbal stem cell deficiency; CC, cicatricial conjunctivitis; RR, radiation retinopathy; CP, corneal perforation; TK, tectonic keratoplasty; AMT, amniotic membrane transplant; G1, grade 1 (well-differentiated); G2, grade 2 (moderately differentiated); G3, grade 3 (poorly differentiated).
The interval between the completion of radiotherapy and the first post-radiotherapy ophthalmic visit.
The interval between the completion of radiotherapy and the onset of self-reported post-radiotherapy symptoms.