Figure 2.

Species-specific inhibition of PKR by K3 orthologs. HeLa-PKRkd cells were transfected with expression vectors encoding firefly luciferase (0.05 μg), PKR from the indicated species (0.2 μg) and VACV K3L or CaPV K3L orthologs (0.4 μg). Luciferase activities were measured 48 hours after transfection and normalized to PKR-only transfected cells to obtain relative luciferase activities. Results shown are representative of three independent experiments.