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. 2021 Mar 19;13:2669–2680. doi: 10.2147/CMAR.S275352

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© 2021 Guo et al.

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PROX1-AS1 promotes cell growth, invasion and inhibits apoptosis by targeting miR-877-5p/PD-L1 axis. (A) The RT-qPCR assay was implemented to certify transfection efficiency for miR-877-5p inhibitor and sh-PD-L1. (B–E) CCK-8, colony formation, flow cytometry, and transwell assays were employed to estimate the role of PROX1-AS1/miR-877-5p/PD-L1 axis in GC cell proliferation, migration, invasion and apoptosis. **P < 0.01, ***P < 0.001 vs NC inhibitor group. ^#P < 0.01, ^##P < 0.05 vs miR-877-5p inhibitor group.