Table 2.

Meta-regression analysis of overall survival (OS).

Covariates	HAIC as palliative treatment (10 studies)				HAIC as adjuvant treatment (7 studies)
	Exponentiated coefficient	95% CI&	P	Tau2	Exponentiated coefficient	95% CI&	P	Tau2
Univariate analysis
Treatment regimens	0.25	−0.29 to 0.79	0.323	0.026	0.49	−0.65 to 1.63	0.32	0.068
Sample size	0.16	−0.62 to 0.94	0.646	0.025	0.30	−1.09 to 1.69	0.60	0.108
Methodology quality	0.30	−0.21 to 0.82	0.212	0.026	0.87	−0.55 to 2.29	0.18	0.114
Multivariate analysis
Treatment regimens	0.01	−0.55 to 0.53	0.95	NA	0.56	−1.28 to 2.34	0.40	NA
Sample size	0.09	−0.46 to 0.64	0.71	NA	0.11	−1.86 to 2.08	0.87	NA
Methodology quality	0.08	−0.55 to 0.38	0.67	NA	0.33	−1.85 to 1.18	0.54	NA
Omnibus test for moderators			0.64	0.04			0.72	0.149

^&CI, Confidence Intervals; NA, Not Applicable.