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. Author manuscript; available in PMC: 2021 May 1.
Published in final edited form as: Nat Rev Genet. 2020 Jul 14;21(11):699–714. doi: 10.1038/s41576-020-0254-8

Figure 3 |. Number of transcription factor binding sites without functional assignment versus number of transcription factor regulatory sites in E. coli.

Figure 3 |

The sum of transcription factor binding sites (TFBSs) without functional assignment (purple) and transcription factor regulatory sites (TFRSs; yellow) represent the complete set of TFBSs. The figure was drawn using data from published chromatin immunoprecipitation (ChIP) experiments and data from classical experiments128,212–220. Only TFs with non-functional sites found by highthroughput methodologies were included. A logarithmic scale is used to help visualize the disparate numbers of sites known for Fur and Cra and other TFs, such as DpiA and TrpR.