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Ki-67 expression at matched biopsy sites were compared before and after 3 months of oral LP treatment. A total of 48 paired biopsies were available for evaluation. A) On average, 3 months of LP decreased Ki-67 LI by 55% (13.8 ± 3.50 at baseline versus 6.25 ± 1.36 at 3 months). Columns, mean; bars, SEM. *, P < 0.041. Representative photomicrographs of matched bronchial Ki-67 IHC staining B) before treatment, C) after 3 months of oral LP; magnification: 400×.
