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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: Microcirculation. 2020 Sep 4;28(1):e12653. doi: 10.1111/micc.12653

Figure 2.

Figure 2.

Chronic TPPU treatment improved endothelium-dependent dilation in PAs without changing myogenic tone. TPPU treatment had no effect on myogenic tone (A) but improved carbachol-mediated dilation (B). TPPU treatment reduced the sensitivity of the PAs to SNP (C) without affecting the dilation induced by calcium channel blockade (D). Concentration response curves were compares by two-way ANOVA, p values and the number of replicates are indicated on individual graphs. Myogenic tone generation was compared by a Student’s t-test, the p value and the number of replicates is indicated on the graph.