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TPPU treatment increased the mRNA expression of markers of neurogenesis and neuronal support. mRNA expression was assessed in the brain by qRT-PCR using Taqman primers. The expression of doublecortin mRNA was increased (A) while the expression of synaptophysin mRNA was unchanged (B). The expression of BDNF mRNA was increased by TPPU treatment (C). Data was compared using a Mann-Whitney nonparametric t-test, p values and replicate numbers are shown on each graph.
