Figure 5.
TPPU increased the mRNA expression in the brain of sEH, TNF-alpha and SOD3 without changing the expression of arginase 1. mRNA expression was assessed in the brain by qRT-PCR using Taqman primers. The expression of the mRNA for sEH was increased in TPPU treated rats (A), while the mRNA for arginase 1 was unchanged (B). The mRNA expression of TNF-alpha and SOD3 were both increased in the brains of TPPU treated rats compared to vehicle (C and D). Data was compared using an unpaired Student’s t-test, P values and replicate numbers are shown on each graph.