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. Author manuscript; available in PMC: 2022 Feb 1.
Published in final edited form as: Contemp Clin Trials. 2021 Jan 12;101:106278. doi: 10.1016/j.cct.2021.106278

Table 3:

Expected 95% Confidence Intervals (CI) for diseases assuming a range of prevalence for an assumed sample size of evaluable subjects of 1500

Disease prevalence 0.05 0.1 0.15 0.2 0.25
# Cases 75 150 225 300 375
PPA 0.85 0.85 0.85 0.85 0.85
95% CI Lower (PPA) 0.769 0.793 0.803 0.810 0.814
95% CI Upper (PPA) 0.931 0.907 0.897 0.890 0.886
NPA 0.8 0.8 0.8 0.8 0.8
95% CI Lower (NPA) 0.779 0.779 0.778 0.777 0.777
95% CI Upper (NPA) 0.821 0.821 0.822 0.823 0.823