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. 2021 Jan 20;5(3):e10450. doi: 10.1002/jbm4.10450

Fig 2.

Fig 2

Bone parameters in TAM treated Prrx1‐Cre/ERT2 male mice recapitulate anabolic effect in females. Male Prrx1‐cre/ERT2 mice (n = 3) were treated with vehicle or TAM (30 mg/kg i.p. × 5; total dose 150 mg/kg) starting at 4 weeks of age with harvest at 8 weeks. (A) H&E‐stained tibia. (B) μCT reconstructions of the femurs. (C) μCT parameters for trabecular and cortical bones. (D) Real‐time PCR for bone formation marker genes with total RNA from tibial bone. Statistical significance is indicated as follows: *p < .05, **p < 0.01, and ****p < 0.0001.