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. 2021 Mar 24;15(3):e0009271. doi: 10.1371/journal.pntd.0009271

Table 3. Genotype and allele frequencies for each replicate of the CKR x ROCK experiment and their associated Hardy-Weinberg (HWE) and genetic drift p-values.

Gen. Sample size Genotype frequency observed (expected#) Allele frequency HWE (p-value) Genetic drift (p-value)
SS RS RR S R
AF1 90 0.00 1.00 0.00 0.50 0.50 -- --
BF1 90 0.00 1.00 0.00 0.50 0.50 -- --
A1F3 90 0.33 (0.33) 0.48 (0.49) 0.19 (0.19) 0.57 0.43 0.047* 0.000
A1F5 90 0.33 (0.36) 0.53 (0.48) 0.13 (0.16) 0.60 0.40 0.184 0.057^
A1F7 90 0.40 (0.46) 0.51 (0.44) 0.07 (0.11) 0.68 0.32 0.014* 0.000
A1F9 90 0.41 (0.37) 0.38 (0.47) 0.21 (0.17) 0.60 0.40 0.001* 0.000
A2F3 90 0.19 (0.22) 0.57 (0.50) 0.24 (0.28) 0.47 0.53 0.142 0.059^
A2F5 90 0.29 (0.32) 0.56 (0.49) 0.15 (0.19) 0.57 0.43 0.116 0.000
A2F7 90 0.39 (0.41) 0.50 (0.46) 0.11 (0.13) 0.64 0.36 0.046* 0.000
A2F9 89 0.47 (0.53) 0.51 (0.40) 0.02 (0.08) 0.73 0.27 0.002* 0.000
B1F3 90 0.29 (0.27) 0.46 (0.50) 0.26 (0.24) 0.52 0.48 0.340 0.164^
B1F5 90 0.33 (0.36) 0.53 (0.48) 0.13 (0.160 0.60 0.40 0.018* 0.000
B1F7 90 0.47 (0.49) 0.47 (0.42) 0.07 (0.09) 0.70 0.30 0.020* 0.000
B1F9 87 0.60 (0.60) 0.36 (0.35) 0.05 (0.05) 0.78 0.22 0.029* 0.000
B2F3 90 0.42 (0.42) 0.46 (0.45) 0.12 (0.12) 0.65 0.35 0.000* 0.000
B2F5 90 0.44 (0.42) 0.41 (0.45) 0.14 (0.12) 0.65 0.35 0.378 0.506^
B2F7 90 0.54 (0.57) 0.44 (0.36) 0.03 (0.07) 0.75 0.25 0.002* 0.000
B2F9 90 0.68 (0.68) 0.29 (0.29) 0.03 (0.03) 0.82 0.18 0.035* 0.000
Global χ2 (df = 32) = 125.46 237.43
Global p-value = 0.000* 0.000

# Expected genotype frequency values estimated from same generation

* Values out of HWE

^ Unable to reject null hypothesis of allele frequency changes due to genetic drift