Table 3. Mean and (standard deviation) of pulmonary function test and clinical CT scores.
| Ventilation | Parameter | Baseline | 3 Months | 1 Year | 2 Year |
|---|---|---|---|---|---|
| PFT | FEV1% Predicted | 93.54 (7.42) | 93.01 (9.01) | 91.69 (9.95) | 87.85 (10.03) p = 0.06 |
| FVC % Predicted | 101.44 (10.56) | 99.89 (11.70) | 99.67 (11.12) | 95.39 (14.69) p = 0.09 | |
| FEF25-75% predicted | 90.30 (21.93) | 87.83 (26.71) | 85.47 (22.67) | 83.61 (20.80) | |
| Clinical Scores | Brody ATS | 26.19 (13.52) | 29.81 (16.10) | 30.58 (14.66) | 33.10 (14.36) * |
| Brody BS | 5.84 (8.21) | 5.46 (7.37) | 5.93 (6.67) | 7.29 (7.20)* | |
| Brody MPS | 2.90 (5.04) | 3.63 (5.36)* | 5.87 (7.28)* | 7.03 (8.06)* |
Note: Pairwise differences in the follow-up PFT measurements and clinical scores from the baseline were tested using the non-parametric Wilcoxon rank rum test. Significance at the 0.05 p-value are indicated as *. P-values are stated for p<0.1 in the table. Brody ATS = Brody air trapping score, Brody BS = Brody bronchiectasis score, and Brody MPS = Brody mucus plugging score. We used all subjects (N = 36) from both Site 1 and Site 2 in this study.