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RPE-MYC cells were captured after treatment with vehicle control, 5 μM diMF or 10 μM fasudil. The grey arrow at time 01:40 denotes a diMF treated cell delayed in mitosis compared to vehicle control cells or cells treated with the ROCK inhibitor fasudil. The black arrow at time 03:20 denotes the same cell which eventually did complete mitosis but failed to complete cytokinesis. The resulting cell was bi-nucleate (4n).
