Table 1. Homogeneity and comparison of demographic and characteristics data between groups.
| Survivor Group n = 7 | Non—Survivor Group n = 7 | p-value | |
|---|---|---|---|
| Sex (Male) | 4 (57%) | 7 (100%) | 0.192 |
| Sex (Female) | 3 (43%) | 0 (0%) | |
| Age (years) | 64 (60; 73) | 71 (57; 72) | 0.797 |
| Weight (kg) | 74 (68; 78) | 85 (75; 99) | 0.085 |
| SOFA | 3 (2; 6) | 8 (3; 9) | 0.032 |
| RASS | -4 (-4; -2) | -5 (-5; -4) | 0.021 |
| CRP (mg.dl-1) | 51 (2.2; 197) | 112 (26; 309) | 0.482 |
| IL-6 (pg.ml-1) | 145 (111; 567) | 963 (702; 1350) | 0.055 |
| Procalcitonin (ng.ml-1) | 0.6 (0.37; 0.65) | 0.33 (0.12; 0.68) | 0.370 |
| Midazolam | 3 (43%) | 5 (71%) | 0.592 |
| Propofol | 4 (57%) | 1 (14%) | 0.266 |
| Dexmedetomidine | 2 (29%) | 2 (29%) | 1.000 |
| Fentanil | 2 (29%) | 1 (14%) | 1.000 |
| Remifentanil | 0 (0%) | 2 (29%) | 0.462 |
| Morphine | 3 (43%) | 4 (57%) | 1.000 |
| Lidocaine | 3 (43%) | 1 (14%) | 0.559 |
| Neuromusc. blockade | 1 (14%) | 6 (86%) | 0.029 |
| Noradrenaline | 0 (0%) | 3 (43%) | 0.192 |
| Dobutamine | 1 (14%) | 0 (0%) | 1.000 |
| VCV mode | 3 (43%) | 6 (86%) | 0.266 |
| PCV mode | 4 (57%) | 1 (14%) | |
| FiO2 | 0.7 (0.7; 0.8) | 1 (0.8; 1) | 0.009 |
| Tidal Volume (ml) | 470 (450; 480) | 480 (450; 520) | 0.478 |
| Resp. rate (rpm) | 18 (18; 20) | 20 (18; 20) | 0.375 |
| PEEP (cmH2O) | 8 (6; 10) | 10 (9; 12) | 0.032 |
| PaO2 (mmHg) | 143 (95.6; 301) | 124 (81.2; 137) | 0.225 |
| ANIm | 64 (53; 74) | 93 (89; 99) | 0.003 |
| ANIi | 64 (57; 76) | 94 (87; 99) | 0.006 |
| Energy (ms) | 0.57 (0.3; 0.63) | 0.18 (0.13; 0.71) | 0.225 |
Basic descriptive and tests for the demographic and characteristics variables for each group. Absolute (N) and relative (%) frequencies for the qualitative variables, and median and quartiles (1st; 3rd) for the quantitative variables. P-values were calculated using Mann—Whitney U test. SOFA, Sequential Organ Failure Assessment; RASS, Richmond Agitation-Sedation Scale; CRP, C-reactive protein; IL-6, Interleukin-6; VCV, Volume-controlled ventilation; FiO2, Fraction of inspired oxygen; PEEP, positive end-expiratory pressure; PaO2, partial pressure of oxygen in arterial blood; ANIm, mean analgesia nociception index; ANIi, instantaneous analgesia nociception index.