Table 4.

Effects of fetal alcohol exposure on histone acetylation mechanism.

Study	Species	Exp.	Region	Genes	Mark(s)	Findings
(Govorko et al., 2012)	Sprague Dawley rats	Liquid diet	Arcuate area / Hypo.	Cbp, Hdac2	H3K9ac	Decrease of Cbp and increase Hdac2, decreased H3K9ac
(W. Guo et al., 2011)	Long-Evans	Vapor	Cereb.	CBP	H3K914ac, H3K23ac H4ac	Decreased CBP, H3K9/14ac, H3K23ac, and H4ac
(Subbanna et al., 2015)	C57BL/6	i.p. 2.5 g/kg	NeocortexHipp	Cb1	H4K8ac	Increased H4K8ac at Cb1 gene
(Veazey et al., 2015)	C57BL/6	i.p. 2.9 g/kg	Cortex	24 genes	H3K9ac	Increased H3K9ac associated with promoters of growth factor genes in offspring effected by craniofacial deformities

Abbreviations, Exp. = exposure, i.p. = intraperitoneal, vapor = ethanol vapor, cereb = cerebellum, hipp = hippocampus