Fig. 3.

Using CTD Anatomy to identify organ toxicities. The numbers and distribution of unique chemicals, phenotypes, and chemical-phenotype dyads are shown for liver, kidney, brain, and heart. Venn analysis discovers unique and shared data types for each anatomical location, such as ambient air pollutants (carbon monoxide, ozone, nitrogen dioxide, soot, sulfur dioxide, vehicle emissions, and particulate matter) affecting different subsets, and environmental chemicals (sodium arsenite, cadmium, bisphenol A) affecting toxicities related to basic cellular metabolism in all four organs.