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. 2021 Mar 24;7(13):eabd2368. doi: 10.1126/sciadv.abd2368

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Copyright © 2021 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).

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Fig. 8 — A schematic showing an overview of ATP1A3-related disorders as ion channel diseases throughout the human life span, together with other known genes, based on the latest knowledge (29). The x axis approximately (not linearly) shows the life span of a human, from newborn to adulthood. The y axis represents disease severity. MCD, malformation of cortical development; DEE, developmental and epileptic encephalopathy.