Table 1.
Clinical characteristics of chronic DoC patients and HCs.
| Metabonomics | Lipidomics | |||||||
|---|---|---|---|---|---|---|---|---|
| Characteristics | HCs | VS | MCS | P value | HCs | VS | MCS | P value |
| Patients (n) | 8 | 12 | 11 | / | 32 | 32 | 22 | / |
| Male/Female (n) | 3/5 | 9/3 | 6/5 | 0.157 | 23/9 | 25/7 | 12/10 | 0.170 |
| Age (years) | 55.4 ± 4.2 | 63.8 ± 9.6 | 63.2 ± 7.9 | 0.323 | 48.3 ± 14.2 | 48.4 ± 15.4 | 52.2 ± 12.5 | 0.575 |
| GCS | / | 6.8 ± 1.3 | 8.8 ± 1.5 | 0.003 | / | 7.8 ± 1.2 | 10.8 ± 1.8 | 0.413 |
| CRS-R | / | 5.1 ± 1.3 | 10.6 ± 5.7 | <0.001 | / | 4.2 ± 1.8 | 13.1±4.6 | <0.001 |
| Cause | / | TBI | TBI | / | / | TBI | TBI | / |
Continuous variables are expressed as the mean ± standard deviation (SD); TBI: traumatic brain injury; GCS: Glasgow Coma Scale; CRS-R: Coma Recovery Scale-Revised scores; DoC: disorders of consciousness; HCs: healthy controls; VS: vegetative state; MCS: minimally conscious state.