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. Author manuscript; available in PMC: 2021 Mar 24.
Published in final edited form as: Neurobiol Dis. 2020 Oct 10;146:105129. doi: 10.1016/j.nbd.2020.105129

Fig. 4.

Fig. 4.

Proteins with significant race x diagnosis interactions in each region. Venn diagram showing the regional overlap in proteins with significant race x diagnosis interactions (p < 0.05), and plots showing examples of these proteins in different regions: heteronuclear ribonucleoprotein D0, α-2-macroglobulin, α-synuclein, and fructose-bisphosphate aldolase A. The plots show log10 TMT intensities plotted for each brain sample in the relevant region. Each data point represents one individual; brains of non-Hispanic White CN adults are filled circles, brains of non-Hispanic White AD adults are open circles, brains of African American/Black CN adults are filled triangles, and brains of African American/Black AD adults are open triangles. Horizontal lines indicate group averages (N = 5 per group, except N = 3 for hippocampus from African American/Black CN adults, N = 4 for IPL and GP African American/Black CN and GP African American/Black AD adults). * indicates p < 0.05. Abbreviations: AA, African American/Black; CN, cognitively normal; NHW, non-Hispanic White; AD, Alzheimer’s disease; IPL, inferior parietal lobule; GP, globus pallidus.