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. 2021 Mar 17;2021:8884243. doi: 10.1155/2021/8884243

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Copyright © 2021 Seul-Ki Kim et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

The effects of HemoHIM on mRNA expression of (a) ChAT, (b) AchE, (c) mAchR M1, (d) mAchR M2, (e) BDNF, (f) TrkB, (g) CREB, (h) Erk1, and (i) Erk2 in the scopolamine-induced model. The mRNA expression was measured by RT-PCR using specific primers. β-actin levels were compared for the equal loading control. Quantitative analysis of relative expression for BDNF/β-actin was represented as graph. The data are expressed as the mean ± S.E.M. (n = 4∼5 per group). Significant difference from control group (###P < 0.001) and from scopolamine-treated group (^∗∗∗P < 0.001, ^∗∗P < 0.01, ^∗P < 0.05).