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. Author manuscript; available in PMC: 2021 Aug 24.
Published in final edited form as: Nature. 2021 Feb 24;591(7851):615–619. doi: 10.1038/s41586-021-03272-1

Figure 2 |. Novelty reorganizes vHPC activity patterns.

Figure 2 |

a, Left, normalized LFP examples. Right, vHPC theta power during novelty (novel: 14, familiar: 16 mice; Mann-Whitney test, P = 0.001). Inset, average theta power of each mouse. b, Left, the ratio of vHPC units phase-locked to local theta oscillations (Chi-square test, P = 0.03; novel: 29, familiar: 26 cells). Right, vHPC unit firing rate in the novel group (Mann-Whitney test, P = 0.04). Cumulative distribution shows all single unit values. c, Left, examples showing normalized theta filtered LFP and vHPC single-unit spikes (ticks). Right, preferred theta phases at which vHPC units fired (Kolmogorov-Smirnov test, P = 0.01). * P < 0.05. ** P < 0.005. Data are represented as mean ± SEM.