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Characteristics of fabricated microspheres
| Formulation | Mean diameter (μm) | Theoretical siRNA (2.0 mg MS) | Avg. actual siRNA (2.0 mg MS) | Avg. EE (%) |
|---|---|---|---|---|
| Empty-MS6 | 5.4 ± 2.0 | -- | -- | -- |
| siRNA-MS6 | 5.0 ± 1.7 | 4.44 μg | 3.75 μg | 84 ± 7 |
| Empty-MS10 | 6.5 ± 2.9 | -- | -- | -- |
| siRNA-MS10 | 3.8 ± 1.8 | 2.67 μg | 2.13 μg | 85 ± 9 |
