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. 2020 Mar 12;25(2):147–155. doi: 10.1016/j.bjpt.2020.03.002

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© 2020 Associação Brasileira de Pesquisa e Pós-Graduação em Fisioterapia. Published by Elsevier Editora Ltda. All rights reserved.

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Effects of osteoarthritis and resistance training on matrix metalloproteinase-2 activity in the quadriceps and patellar tendon of rats. (A) Rat model of osteoarthritis (exposed to anterior cruciate ligament injury). (B) Rat model of osteoarthritis with resistance training (consisted of climbing a vertical ladder with weights secured to the tails). Yellow oval represents matrix metalloproteinase-2 (MMP-2). (↑) Up-regulated MMP-2 activity and (↓) down-regulated MMP-2 activity. The figure was created in the Mind the Graph platform (www.mindthegraph.com). The image from Mind the Graph, http://mindthegraph.com/, is licensed under the Attribution-Share Alike 4.0 International license.