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. 2021 Mar 11;12:559925. doi: 10.3389/fimmu.2021.559925

Figure 1.

Figure 1

SCA patients in VOC (Inline graphic) condition show an anti-inflammatory cytokine profile, when compared to StSt (Inline graphic) and HD (Inline graphic) groups. Statistically significant values were considered when p < 0.05, and are presented as *p < 0.05; **p < 0.01; ***p < 0.001. Chemokines (A), cytokines (B) and growth factors (C) were measured using Luminex, and anaphylatoxins (D) measured using CBA. Data is presented as median values and interquartile range in pg/ml. Statistical analysis was performed using Kruskal-Wallis and Dunn's Multiple Comparison Test. HD, healthy donors; StSt, Steady-state; VOC, vaso-occlusive crisis.