Table 2.
Laboratorial data of hematological parameters from HD, StSt, VOC and CV groups.
| Variables | HD n = 53 | StSt n = 27 | VOC n = 22 | CV n = 22 | p-value |
|---|---|---|---|---|---|
| RBC (×106/μL, median [IQR]) | 4.99[4.59–5.40] | 2.51[2.19–2.75] | 2.39[2.09–2.94] | 2.65[2.29–3.12] | <0.0001a,b |
| Hemoglobin (g/dL, median [IQR]) | 14.90[13.55–15.95] | 8.0[7.10–9.0] | 7.50[6.20–8.45] | 8.30[7.20–8.70] | <0.0001a,b |
| Hematocrit (%, median [IQR]) | 43.70[40.45–47.30] | 24.50[21.70-28.50] | 22.0[18.60–25.0] | 24.80[21.95–26.68] | <0.0001a,b,d |
| MCV (fL, median [IQR]) | 87.80[84.85–90.4] | 99.90[92.80–110.2] | 91.30[79.60–99.80] | 90.55[86.83–99.15] | <0.0001a,c |
| MCH (pg, median [IQR]) | 29.70[28.90–30.60] | 32.10[30.30–36.70] | 31.10[27.35–33.20] | 29.70[27.58–34.03] | 0.0008a |
| MCHC (g/dL, median [IQR]) | 34.10[33.10–34.60] | 32.70[31.90–34.10] | 33.60[32.90–34.05] | 33.15[32.40–33.95] | 0.0057a |
| RDW (fL, median [IQR]) | 13.70[12.95-13.95] | 18.20[17.30–19.80] | 21.20[19.65–23.80] | 19.95[18.08–22.90] | <0.0001a,b |
| Reticulocyte (×103/μL, median [IQR]) | 72.70[56.90–88.80] | 367.6[226.0–529.9] | 257.4[134.3–349.2] | 248.6[134.5–332.8] | <0.0001a,b |
| WBC (×106/μL, median [IQR]) | 6.33[5.27–7.10] | 7.42[5.95–9.44] | 11.39[8.82–15.17] | 9.51[8.07–11.38] | <0.0001b,c |
| Neutrophil (x103/μL, median [IQR]) | 3.43[2.80–4.18] | 3.39[2.13–4.81] | 6.90[4.87–9.46] | 4.88[3.05–6.43] | <0.0001b,c,d |
| Lymphocyte (v103/μL, median [IQR]) | 1.84[1.55–2.16] | 2.41[2.13–3.36] | 3.02[2.32–4.78] | 3.28[2.43–4.96] | <0.0001a,b |
| Monocyte (×103/μL, median [IQR]) | 0.38[0.29–0.41] | 0.43[0.33–0.69] | 0.66[0.52–0.86] | 0.60[0.41–0.83] | <0.0001b,c |
| Basophil (×103/μL, median [IQR]) | 0.03[0.02–0.05] | 0.03[0.03–0.05] | 0.00[0.00–0.03] | 0.00[0.00–0.04] | 0.0002b,c |
| Eosinophil (×103/μL, median [IQR]) | 0.19[0.12–0.41] | 0.24[0.13–0.50] | 0.22[0.10–0.62] | 0.42[0.24–0.62] | 0.6031 |
| Platelet count (×103/μL, median [IQR]) | 244[213–281.5] | 420[372–533] | 411[326–530] | 460.5[339.8–642.0] | <0.0001a,b |
a
Significant difference for HD vs. StSt.
b
Significant difference for HD vs. VOC.
c
Significant difference for StSt vs. VOC.
d
Significant difference for VOC vs. CV. Statistical analysis performed using Kruskal-Wallis with Dunn's Multiple Comparison Test in order to compare HD, StSt and VOC. In addition, Wilcoxon test was performed for VOC and CV comparison. For both analyses, p was considered significant when <0.05.
Bold-type font indicates statistical significance.