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. 2021 Mar 25;188(4):137. doi: 10.1007/s00604-021-04766-5

Table 3.

Comparison of different methods used for the detection of SARS-CoV-2

Method Sample type LOD Reference
1 RT-PCR Viral -RNA 0.91 copies/mL [30]
2 RT-PCR RdRp gene 3.6 copies/reaction [7]
3 Field effect transistor S-protein antibody 16 copies/mL [31]
4 RT-LAMP mRNA 50 copies/μL [33]
5 RT-q(PCR-LAMP) mRNA 5 copies/reaction [34]
6 ITP-Crisper cDNA of mRNA 10 copies/μL [35]
7 Molecular POC mRNA 10 copies/μL [36]
8 Electrochemical Viral antigen 0.8 pg/mL [37]
9 Lateral flow immunoassay IgM/IgG 1 pg/mL [38]
10 Fluorescence Protease 0.9 copies/mL [This study]