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. 2021 Mar 24;12(4):312. doi: 10.1038/s41419-021-03598-8

Fig. 5. Sox2, Klf4, CD133 and CD15 were expressed in GBM under hypoxia.

Fig. 5

A, B Assessment of samples from the CGGA database showed that Sox2 and Klf4 were expressed in GBM. C GBM cells exposed to 21% O2 and 1% O2 for 72 h showed that Sox2, Klf4, CD133 and CD15 levels increased significantly in 1% O2 when compared with control cells in 21% O2. D, E There was a lower expression of Sox2, Klf4, CD133 and CD15 under normoxia, while these proteins increased significantly under hypoxic conditions. P values were determined by the independent samples t test.